Buffalo based quartet Aqueous continue to impress fans with every move, playing some of the best live performances that captures the group’s unique penchant for songwriting. The band will continue to capitalize on that effect, as they just kicked off an extensive fall tour and will release a brand new album, Best In Show, next Friday October 14th.On Best In Show, the quartet expertly displays their unique ability for meticulously crafted arrangements with soulful lyrics and a dynamic musical range, while maintaining their signature dual rock guitar onslaught, anthemic choruses, melodic synth lines, and a tight rhythm section that always gets the party going. Guitarist/vocalist/keyboardist David Loss speaks to the excitement captured on Best In Show, saying, “Although Aqueous is primarily a live touring band, I feel that we all work very well in the studio environment; you can be creative in different ways and I like that the possibilities are endless. Personally, recording ‘Best In Show’ was a unique experience because I got to really explore my role on keyboards more than I ever had previously, and it was cool to challenge myself like that, and also to utilize some classic instruments to capture the sounds I was hearing just right. Ultimately, if someone had never heard Aqueous, I’d definitely give them ‘Best In Show’ because it showcases so much of what we have to offer as a band.”Each track on the four-song EP showcases a diverse and powerful side to the band’s ever-evolving sound. “I really like the song selections on this EP, they encompass the many facets of the band’s sound,” said bassist Evan McPhaden, “We touched on soul, pop, prog, dance and rock which makes for a really fun and enjoyable listen.”With Aqueous out on the road and Best In Show coming out shortly, the band has offered up a very first taste of the new release. We’re excited to offer up a stream of “Random Company,” which you can hear below.Now that rocks! Drummer Rob Houk shares his take on Best In Show, saying “As the new guy in Aqueous, I was enthralled with how much focus, dedication and care that goes into AQ’s studio process, and I couldn’t be happier or more excited with this album and to make music with such a great crew.”Guitarist Mike Gantzer says, “I’m really proud of the work we did on this project, it feels like a definitive step forward in our band’s sound, and the vibe is really great on the whole album, which I attribute to the fact that the vibe was really great while we were making it! Everyone in the band crushed their parts and stepped their game up, and I think the sound is really cohesive throughout. We had a blast and put our all into making Best In Show, and I’m psyched for people to get down with it.”Fortunately, fans can get down with Aqueous throughout the fall, as the band is touring extensively in support of Best In Show. The band will celebrate the album’s release with a two night run at their hometown Buffalo Iron Works venue, with support from BIG Something and Natalie Cressman on October 13-14 respectively. All tour and album details can be found on the band’s website, and a teaser for the album as well as the full tour schedule can be viewed below.
In recent years investigators have discovered that breast tumors are influenced by more than just the cancer cells within them. A variety of noncancerous cells, which in many cases constitute the majority of the tumor mass, form what is known as the “tumor microenvironment.” This sea of noncancerous cells and the products they deposit appear to play key roles in tumor pathogenesis.Among the key accomplices in the tumor microenvironment are mesenchymal stem cells (MSCs), a group of adult progenitor cells, which have been shown to help breast cancers maneuver and spread to other parts of the body.Now, new research sheds further light on how this spreading is happening. Led by investigators at Harvard-affiliated Beth Israel Deaconess Medical Center (BIDMC), the research demonstrates that the lysyl oxidase (LOX) gene is spurred to production in cancer cells as a result of their contact with MSCs, and once produced, can help ensure the spread of otherwise weakly metastatic cancer cells from primary tumors to the lung and bones. Described online in the Proceedings of the National Academy of Sciences (PNAS), this discovery not only provides key insights into the basic biology of tumor formation, but also offers a potential new direction in the pursuit of therapies for the treatment of bone metastasis.“We don’t have a lot of therapies that can target breast cancer once it has metastasized, particularly once cancer cells have lodged in the bone,” says senior author Antoine Karnoub, an investigator in the Department of Pathology at BIDMC and assistant professor of pathology at Harvard Medical School. “When breast cancer cells reach the skeleton, one way in which they cause damage is by breaking down bone tissue, which results in the bone’s rich matrix releasing numerous factors. These factors, in turn, feed the cancer cells, setting in motion a vicious cycle that leaves patients susceptible to fractures, pain, and further metastasis.”MSCs are nonhematopoietic progenitor cells predominantly produced in the bone marrow that generate bone, cartilage, fat, and fibrous connective tissue. They additionally support immune cell development and are recruited to inflammatory sites throughout the body to help shut down immune responses and regenerate damaged tissues, as might occur during wound healing. Several years ago, as a postdoctoral researcher at the Whitehead Institute of the Massachusetts Institute of Technology, Karnoub began exploring the idea that MSCs were migrating to tumors after mistaking the cancer sites for inflammatory lesions in need of healing.“We discovered that once MSCs had reached the tumor sites, they were actually helping in cancer metastasis, causing primary cancer cells to spread to other sites in the body,” he explains. In this new research, Karnoub wanted to find out — in greater molecular detail — how breast cancer cells respond to the influences of MSCs in order to better understand how cancer cells cross talk with recruited cells in the microenvironment.His scientific team first embarked on a straightforward experiment. “We took two dishes of cells, cancer cells and MSCs, and mixed them together,” Karnoub explains. After three days, the researchers removed the cancer cells and studied them to see how they had changed.“We found that the lysyl oxidase gene was highly upregulated in the cancer cells,” Karnoub says. “It turns out that when a cancer cell comes in contact with an MSC, it flips on this LOX gene, turning it up by a factor of about 100. So our next question was: What happens to the cancer cells when they encounter this boost of LOX that they themselves have produced?”The answer, as revealed in subsequent experiments, was that LOX was setting in motion a cell program called epithelial-to-mesenchymal transition (EMT). During EMT, cancer cells that usually clump together undergo a transformation into cells that exhibit decreased adhesion to their neighbors and go their own way. As a result, these cancerous cells are able to migrate, significantly enhancing their ability to metastasize.“When we put these cells back into mice, they not only formed tumors that metastasized to the lung, but also to the bone,” says Karnoub. “This makes you wonder whether the cancer cells in primary tumors have become so acclimated to interacting with bone-derived MSCs that they can now grow more easily in the bone once they leave the tumor.”The investigators also wanted to find out if, by going through the EMT process, cancer cells were also acquiring the phenotypes of another highly aggressive feature of malignant cancer cells, those of cancer stem cells within the cores of most tumors.“Cancer stem cells are believed to be responsible for the resurgence of tumors following chemotherapy treatment, and an increasing body of science is focused on understanding how CSCs function and how they originate,” says Karnoub. “The processes of EMT and CSC formation have been described as being closely coupled, and we asked whether LOX might be regulating CSC phenotypes, just as it was regulating EMT. To our surprise, this was not the case. This tells us that pathways that were once thought to be intimately intertwined and commonly tweaked may, in fact, be separate, and now we can start to tease out the respective circuitries with a bit more clarity.”Lastly, the investigators identified the mechanism that was enabling LOX to be turned on from outside the cell, a set of molecules called hyaluronic acid (HA) and CD44. “It turns out that the MSCs provide the HA while the cancer cells provide the CD44, and they work in tandem like a lock and key to upregulate LOX expression,” explains Karnoub, adding that antagonists to HA and CD44, already in extensive investigations and clinical exploration, might be of increased use from a clinical standpoint, perhaps in managing bone metastasis.To read the full story.
Regarding live entertainment, five performances will also be held at The Highland Center. The Little Switzerland Cloggers kick off the shows with a free performance at 1:00 p.m. on Saturday, March 14th. Then, award-winning banjoist and dancer, Tyler Hughes, presents old time music at 3:00 p.m. To round out the night, Bill Jenkins and the Virginia Mountain Boys perform folk music of the Appalachian Mountains at 7:00 p.m. The Highland Center in Monterey will have an expanded presence at the festival this year, hosting the Highland County Visitor Center for festival information, children’s activities, vendors, and a “Maple Taproom,” featuring a place to sit down and enjoy an adult beverage, including the 2020 Daylight Cravings: Maple Bacon Breakfast Stout from Brothers Craft Brewing. On Saturday, March 21st, John Bullard plays classical banjo at 3:00 p.m., followed by the all-female trio, The official maple festival of Virginia returns with new experiences After Jack, with their popular “hot folk” performance. Admission to the Saturday 3:00 p.m. shows is $3, or a maple leaf keychain, and the Saturday 7:00 p.m. shows is $10. These four performances are brought to the public by the Highland County Arts Council and are made possible in part by funding from the Virginia Commission for the Arts, the National Endowment for the Arts, and the Community Foundation of the Central Blue Ridge. In addition, Hull’s Hideaway Restaurant and Tavern in Monterey will host the acoustic blues trio, Delta Junction, in a 21+ show on Saturday, March 21st at 9:00 p.m. for $10. The tradition of the annual Highland County Maple Festival returns March 14-15 and 21-22, 2020. Since 1958, visitors have been drawn to Highland County to tour real maple sugar camps for a cultural and culinary adventure. All-you-can-eat pancake and buckwheat cake meals, over 100 arts & crafts vendors, and live entertainment make this county-wide event a fun outing with lasting memories for the entire family. Many additional activities can be found on stops while driving around the countryside that features expansive scenic views. These activities include feeding of live fish at the Virginia Trout Company north of Monterey, reliving history with a Highland Museum exhibit at The Mansion House in McDowell, viewing additional vendors at The Church at the Old Oak in Meadowdale, experiencing a local restaurant or store, or enjoying hard craft cider at Big Fish Cider Co. in downtown Monterey. Local civic clubs and organizations feature delicious food, including those famous fresh maple doughnuts, pancake and buckwheat meals with sausage and gravy, trout sandwiches, pork rinds and just about anything maple-flavored! Additional food vendors on Water Street in Monterey offer treats like maple-bacon cupcakes, maple fudge, maple-bacon dates and brewery crafted nachos with maple. Traditional hours of the festival include Saturdays from 9:00 a.m. to 5:00 p.m. and Sundays from 9:00 a.m. to 5:00 p.m., though visitors can get a jumpstart to the day with an all-you-can-eat pancake meal as early as 7:00 a.m. More details on all the festival happenings can be found at www.highlandcounty.org/events/maple-festival or www.facebook.com/HighlandCounty. This year, the Maple Festival features nine unique camps open for the public to tour at no charge. Visitors have the chance to view traditional and modern techniques for creating maple syrup from tree to bottle. In addition to pure maple syrup, some local camps offer a variety of flavored maple syrups infused with native plants or aged in spirit barrels, as well as hickory syrup. New for 2020, Tonoloway Farm is a walk-in, first-generation syrup operation on the wooded slopes of Bullpasture Mountain, just east of McDowell. In addition to wood-fired maple syrup, Tonoloway Farm plans to offer walnut syrup for yet another diverse taste of the Appalachian forests. Over 100 juried arts & crafts vendors will be available in Monterey and McDowell, providing one-of-a-kind treasures, tasty treats, and special gifts. Browse and shop with new and returning vendors for a seemingly endless variety of handcrafted items, from exclusive artwork to exquisite jewelry. Admission to access vendors at the Highland High School and Elementary School gyms remains at $3, which comes with a collectible 2020 maple leaf keychain that also provides entry to both Saturdays’ 3:00 p.m. entertainment. In 1999, the Library of Congress designated The Highland County Maple Festival a “Local Legacy,” and in 2014, the Governor of Virginia signed a bill into law designating the festival as the “official maple festival of Virginia.” Tens of thousands of visitors arrive in the rural mountain community annually to enjoy the event. The Highland County Maple Festival is coordinated by the Highland County Chamber of Commerce and made possible with the help of countless volunteers and organizations.
By Dialogo January 25, 2012 In 2010, the Brazilian Navy participated in the Joint Warrior 101 exercise off the coast of Scotland, at the Royal Navy’s invitation. The frigate Independência (Amazon class) had an embarked air detachment equipped with a Super Lynx multi-mission helicopter belonging to the 1st Reconnaissance and Attack Helicopter Squadron, headquartered at the São Pedro da Aldeia Naval Air Base in the state of Rio de Janeiro, in the Brazilian southeast. Participation in this international exercise trained Brazilian crews for operations as part of international task forces, like the one currently under way in the waters off the Lebanese coast, where the Brazilian frigate União is the flagship of the United Nations mission in Lebanon, known as UNIFIL. This mission incorporates an embarked air detachment equipped with a Super Lynx aircraft on constant alert at fixed flight stations. The Westland Super Lynx is one of the most versatile aircraft ever made. Its speed and endurance in flights over the open ocean and in convoy operations, equipped with special systems and weaponry, make it one of the most lethal and successful weapons ever used in maritime combat. The Brazilian Navy’s Lynx Squadron is always active and has crews trained to execute specific types of missions. At the time it was created, in 1978, it had five AH-11 (Lynx) aircraft, Brazil being the first foreign customer to receive that model. During the 1990s, Brazil acquired nine new, updated Lynx aircraft, known as Super Lynxes (AH-11A). With the arrival of the Super Lynxes and the updates to the older Lynx models, the aviation unit was designated the 1st Reconnaissance and Attack Helicopter Squadron (HA-1), which in 2010 reached the significant milestone of over 57,000 hours of flying time. Starting from the time a pilot joins the squadron, there are three types of qualifications: pilot qualified in model (PQM); aircraft operational pilot (POA); and aircraft operational commander (COA). When a pilot becomes an operational commander, he can execute any type of ship-based and land-based mission. In an operation like Joint Warrior, the pilot receives information on how he will be utilized, and during the Atlantic crossing, the crew begins to study how they will work together, initiating preparations for the missions to be carried out. Joint Warrior is a different operation; for this reason, it is necessary to study all aspects related to it. Lynx missions worth highlighting include reconnaissance, the launch of MK 46 torpedoes and anti-submarine depth charges, the ability to execute over-the-horizon targeting (OTHT) procedures, and coordinated attack plans against surface targets, as well as fast-roping and the transportation of combat divers. Extremely important for the mission success of the Brazilian Navy’s corvettes and frigates, the HA-1 Squadron can be considered the “eyes and the ears of the fleet,” relying on military personnel trained to engage in combat by day or by night, in any kind of weather, and wherever needed.
Sign up for our COVID-19 newsletter to stay up-to-date on the latest coronavirus news throughout New York An art dealer from Sands Point has been accused of hiding millions she made from selling counterfeit artwork purported to be painted by leading abstract expressionists such as Jackson Pollack, Mark Rothko and Willem de Kooning.Glafira Rosales was arrested Tuesday and charged with filing false tax returns and with failure to disclose an offshore bank account in Spain. Federal prosecutors said the 56-year-old failed to report the at least $12.5 million in income from the sales.“Glafira Rosales gave new meaning to the phrase ‘artful dodger’ by avoiding taxes on millions of dollars in income from dealing in fake artworks for fake clients,” Manhattan U.S. Attorney Preet Bharara said.The case, which was first reported by The New York Times last year, is also the subject of a multimillion-dollar lawsuit.Rosales began selling what were described as previously unknown paintings that had never been exhibited before in the 1990s and from 2006 to 2008, she sold about a dozen of the paintings to two prominent Manhattan galleries for more than $14 million, authorities said.She allegedly said her client had ties to Switzerland and wished to remain anonymous, but was in fact fictitious.Investigators found that art, art history and materials science experts determined that “at least several of the paintings sold by her are counterfeit.”Rosales faces up to five years in prison and a $250,000 fine for failing to disclose the bank account. She will arraigned Tuesday at Manhattan federal court.
Would you ever say “this isn’t working, and I have no idea why” to your boss? Never. To your peers? Probably not. After all, most of us are programmed that failure is not an option.Which is crazy.Lots of good ideas with great potential have failed. Even a few of ours:• Our CUSoup program was based on the idea that credit union marketers love to collaborate – so why not get non-competing CUs from across the country to work together, develop some amazing creative for common promotions, and split all of the creative costs to save money? A few cool individual campaigns resulted, but mostly it turned out that everyone needs something different at different times.• CUup2date was a way for smaller credit unions to affordably update their website and get a new redesign every few years by paying a monthly installment, instead of paying for a full redesign all at once. A few nibbles, but no bites.Both ideas seemed to have plenty of potential, but unfortunately most of the support we received was verbal instead of participatory.So why is it considered taboo to talk about failure?Simply put, our society celebrates success, not failure. Awards go to winners, spotlights follow stars, successful people get promoted. Everyone wants to be seen at their best, and failure is the last thing anyone admits.Even at very close-knit marketing gatherings, failures only get discussed later at night after the wine has been flowing for a while. And it’s the award winners that seem to have the most latitude to talk about what didn’t work – their success is what gives them the freedom to talk about failures.*Marketers are not the only ones to face failure.Athletes know that winning seasons are rare, and therefore to be savored and enjoyed. A baseball player that gets on base more than 3 times out of 10 is considered to be very good at what he does. NBA players only make about half of the shots they take, and only if you include those from the free throw line. Get out past the three point line and those numbers drop dramatically.Researchers, scientists, and inventors are certainly used to running all kinds of tests with mixed results. One of the more famous, Thomas Edison, even has a quote attributed to him (perhaps incorrectly) when questioned about all of his failures:‘Results! Why, man, I have gotten a lot of results! I know several thousand things that won’t work.’(Paradoxically perhaps, the only reason we know of this quote is that Edison did succeed and become famous.)Failures are powerful and valuable if they’re handled correctly.Failures can be incredibly valuable launching points for solving problems, once they are seen as an opportunity for defining and refining goals and success. The next time something doesn’t work, take a step back and ask yourself these questions:What’s worth solving and what’s worth letting go?So your Big Idea crashed and burned. What can you learn from the wreckage? Failure is the perfect time to honestly re-examine both premise and process. Should we keep moving this direction, slice up our one big goal into smaller goals, or simply give ourselves more time? Did we even have the right goals? The answer may not be immediately obvious, but viewing the bigger picture may allow you to see where you are getting bogged down on the details.How can someone benefit from my mistake?At least one researcher is taking Edison’s attitude a step further, asking peers to share their failures, to “learn out loud” as a way to collectively speed up finding solutions. In an era where sharing results are inexpensive and instantaneous, effectively “crowdsourcing Edison’s 10,000 iterations” is a great way to accelerate success without anyone wasting time repeating mistakes someone else has already made.As the above post’s author points out, “We need to allow others to learn from our failures. Maybe our failure is really a stepping-stone to an even more awesome invention than we could have imagined.”(*Then again, there are many times a marketer, if they’re being completely honest, could say “this worked, and I have no idea why.”) 13SHARESShareShareSharePrintMailGooglePinterestDiggRedditStumbleuponDeliciousBufferTumblr,Kent Dicken Kent is CEO / Founder of iDiz, a full-service agency focused on Branding, Websites, and Big Ideas for credit unions that want to grow. He is also one of the authors … Web: cuidiz.com Details
“You can’t fly a bucket truck in winds that exceed 35 miles per hour,” Mr. Orlove said. “Miami is seeing gusts above 40 to 50, but as long as the sustained winds are below that, our crews are able to restore service.”Eta, the 28th named storm of the 2020 season, is forecast to meander over the warm waters of the Gulf for the next day or two, according to the National Hurricane Center. The storm, surrounded by dry air that weakens tropical systems, is no longer expected to strengthen into a hurricane.It could still turn to the northeast, possibly returning to Florida’s Gulf Coast, but the 10 a.m. advisory from the hurricane center showed a much-deteriorated storm. All tropical storm watches and warnings for Southwest Florida were lifted.- Advertisement – The power was out Monday morning for more than 40,000 Florida Power & Light customers, mostly in Miami-Dade, Broward and Palm Beach Counties. The company said nearly 300,000 people lost power on Sunday as the storm approached and most had already had it restored.Crews have been out working to restore power in areas where the sustained winds have died down somewhat, such as in Palm Beach County, said Bill Orlove, a company spokesman.- Advertisement – “If the models are correct and the storm doesn’t move to the north, then it’s just going to get sheared apart, just sitting there in the central Gulf of Mexico,” said Stacy Stewart, a senior hurricane specialist with the hurricane center. “The storm is degenerating before our eyes right now.”There is broad scientific consensus that climate change is one of the central forces behind increasingly extreme weather, including hurricanes, producing worsening floods and more powerful storms. – Advertisement –
The home has waterfront views and is surrounded by tropical palms. Picture: Realestate.com.au The Merrimac house comes alive with pops of colour “I really don’t want to let the home go but Peter and I need to downsize.”Video Player is loading.Play VideoPlayNext playlist itemMuteCurrent Time 0:00/Duration 0:34Loaded: 0%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -0:34 Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedCaptionscaptions settings, opens captions settings dialogcaptions off, selectedQuality Levels720p720pHD540p540p360p360p270p270pAutoA, selectedAudio Trackdefault, selectedFullscreenThis is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window.This is a modal window. This modal can be closed by pressing the Escape key or activating the close button.Close Modal DialogThis is a modal window. This modal can be closed by pressing the Escape key or activating the close button.PlayMuteCurrent Time 0:00/Duration 0:00Loaded: 0%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -0:00 Playback Rate1xFullscreenQuirky ranch with a view!00:34 Related videos 00:34Quirky ranch with a view!01:53Chill out in this underground home00:35Dreamy wooden cabin, Slovenia00:29Multi award-winning treehouse01:24Want more of your view? Get a rotating home!00:37The French reno full of lifeJohnston says she wanted to create a ‘happy home’ where she could entertain guests.“I love colour and while the house is quite neutral I have been able to add a splash of colour to every room,” she says.“This home puts a smile on your face when you walk in.” A handful of European getaways inspired homeowners Pete and Susan Johnston to create a slice of paradise on the Gold Coast.Built almost a decade ago, the waterfront house is situated in the exclusive gated enclave of the Lakelands Golf Course estate and commands the street with its tropical palms. 15 Nicklaus Court is a Mediterranean masterpiece. Picture: Realestate.com.auMore from news02:37Purchasers snap up every residence in the $40 million Siarn Palm Beach North5 hours ago02:37International architect Desmond Brooks selling luxury beach villa1 day ago“Almost every morning I sit outside and enjoy my breakfast and it is just absolute tranquillity,” Susan Johnston says.
The Abu Dhabi Investment Authority (ADIA), Singapore’s GIC, the Canada Pension Plan Investment Board (CPPIB) and Caisse de dépôt et placement du Québec are investing in a UK mobile phone operator.The four investors have joined Brazilian investment bank BTG Pactual in the £3.1bn ($4.78bn) purchase of a 33% stake in the UK’s combined Three and O2 networks.The funds are investing alongside Hong Kong holding company Hutchison Whampoa (HWL), which owns Three and is paying Telefonica £9.25bn for O2 in a deal backed by £6bn in bank finance.GIC and the CPPIB will each invest £1.1bn. The ADIA is investing through its wholly owned Limpart Holdings subsidiary, while Québec’s La Caisse is investing through Ivanhoé Cambridge.The latter said the deal gave it a 12% stake.Mark Jenkins, CPPIB’s senior managing director and global head of private investments, said: “This is an exceptional opportunity to acquire a meaningful stake in what will become a leading mobile operator in the UK, giving us immediate scale in an important sector.“We expect this investment will generate attractive, long-term, risk-adjusted returns.”CPPIB said the deal would close next year, pending EU regulatory approval.
An aerial view of part of Cairns CBD. Picture: Skystock.CAIRNS real estate remains some of the most affordable in the country, in contrast to major metropolitan centres, says Real Estate Institute of Queensland zone chairman Tom Quaid.Mr Quaid’s comments came after a recent report revealed an improvement in housing affordability in Queensland.The 2018 March quarter edition of the Adelaide Bank/REIA Housing Affordability Report also showed the median family income required to meet loan repayments had decreased.The proportion of income required to meet loan repayments dropped from 27.6 per cent in the December 2017 quarter to 27.5 per cent in this year’s March quarter.More from newsCairns home ticks popular internet search terms3 days agoTen auction results from ‘active’ weekend in Cairns3 days ago“Cairns still remains relatively affordable in the scheme of things, both from the perspective of its median house price of just north of $400,000, and in real terms,” Mr Quaid said. “It all comes down to what people are looking for though and whether they are realistic in their expectations. If you are looking for brand-new property with all the mod-cons, then expect to pay more in most cases. “It’s the same when it comes to location, with certain suburbs attracting a premium that can make them feel out of reach. For those that look at property as a building block however, there is still good choice to be had in housing in the $300,000s, particularly when you look at the south side of Cairns and some of our city fringe suburbs.”REIA president Malcolm Gunning (pictured above) said the report found the proportion of median family income required to meet average loan repayments decreased by 0.3 percentage points to 31.3 per cent. He said rental affordability declined in all states and territories except for Western Australia and the Northern Territory, with the proportion of median family income required to meet rent payments increasing by 0.1 percentage points to 24.8 per cent. Mr Gunning said the number of loans also decreased across the country by 16 per cent.“Since the last edition of this report, the east coast residential property market has moved … from a seller’s to a buyer’s market,” he said.